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Configurable Clinical Information Extraction with Agentic RAG: What Works, What Breaks, and Why

2026-06-17 · arXiv: 2606.19602

One-line summary

An AI research paper on Configurable Clinical Information Extraction with Agentic RAG: What Works, What Breaks, and Why.

Engineering notes

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Chinese explanation / 中文解读

中文解读待补充:本站会优先为大语言模型、生成式AI、ChatGPT相关技术、计算机视觉、深度学习等高价值论文补充中文说明。

Original abstract

Patient contexts span hundreds of heterogeneous documents and thousands of structured data points, yet the document-level metadata that AI systems need for retrieval and triage is absent or incomplete. Standard retrieval-augmented generation fails on this data, mishandling temporal reasoning, cross-document dependencies, and missing metadata. We deploy ACIE (Agentic Clinical Information Extraction) at University Medicine Essen: an on-premise agentic RAG pipeline that reasons over complete patient contexts and grounds every answer in source passages for clinician verification. We quantify the metadata gap, trace the architectural decisions it shaped, and evaluate extraction alongside an independent retrospective lymphoma registry study, in which nuclear-medicine physicians verify every extracted value against its cited sources. Across 7,326 judgments, clinicians accepted 96.5\% of extractions, with per-type acceptance ranging from 80\% to 99\%.

5.0Engineering value
7.0Research novelty
4.0Business relevance

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